GLP-1 Agonists: Promising Fertility Treatment with Potential Unknown Effects on Pregnancy and Addiction

According to Sadhu, insulin resistance can disrupt the ovarian cycle, leading to infertility by impacting hormones like estrogen and testosterone as well as the release of eggs from the ovaries. GLP-1 agonists can help reduce insulin resistance and improve fertility in patients. However, the effects of these drugs on pregnancy are still unknown, so patients should discuss any plans for becoming pregnant with their doctors and consider contraceptive strategies.

In recent years, there has been an increase in the use of GLP-1 agonists such as Ozempic and Mounjaro. While these drugs have shown promise in reducing insulin resistance and improving fertility, some patients have reported unexpected side effects such as reduced desire to smoke or drink. Luba Yammine, an addiction researcher, suggests that these side effects may be due to changes in the brain’s reward system that are similar to those seen in addiction.

Addiction research is a growing field, with Christian Hendershot, an addiction researcher, noting that there are limited medications available for treating addiction and that patients often struggle to access them. Furthermore, addiction research receives less funding compared to other diseases. Despite this challenges