The University of Science and Technology Hanoi (USTH) in Vietnam has successfully developed a new drug-carrying material that can kill 75% of bladder cancer cells. Professor Dr. Dinh Thi Mai Thanh and her team created this material, called a “superparamagnetic hybrid,” which is made up of superparamagnetic iron oxide nanoparticles (SPIONs) and hydroxyapatite (HAp), both of which have the ability to increase magnetic heat and deliver anti-cancer drugs effectively.
The SPIONs core of the material is surrounded by HAp, which has pores for drug adsorption. When the material is loaded with the anti-cancer drug 5-FU, it can be used to kill bladder cancer cells. By combining SPIONs with copper (Cu) and 5-FU and applying an external magnetic field, the material releases therapeutic drugs and destroys cancer cells.
Professor Thanh highlighted the synergistic effect of combining magnetic hyperthermia with anti-cancer agents in killing cancer cells. The research team has been working on developing new materials for medical applications, and their latest success with the superparamagnetic hybrid material shows promise for treating various types of cancer.
The team conducted tests on cells to measure the material’s effectiveness in releasing drugs and killing cancer cells. Results showed a 75% reduction in cancer cells after exposure to an external magnetic field. Moving forward, the team plans to conduct more in-depth research on animals and explore treatments for other types of cancer using this technology.
Professor Thanh emphasized the challenges in cancer research in Vietnam, particularly in navigating the complex process of testing new treatments on animals, clinical trials, and gaining approval for human use. Despite these obstacles, she remains dedicated to advancing biomedical research and finding innovative solutions for cancer treatment.
With a background in chemistry, Professor Mai Thanh has spent years researching new materials for various applications, including biomedical and environmental uses. She believes in interdisciplinary collaboration and persistence in pursuing research goals, emphasizing that basic research is essential to drive innovation and application in her field.
In conclusion, Professor Thanh’s team at USTH has successfully developed a new drug-carrying material that can kill 75% of bladder cancer cells by using SPIONs with copper (Cu) and 5-FU under an external magnetic field application method.
