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A startup has secured $10 million in funding to develop the Ovax vaccine, a promising solution aimed at preventing intoxication and drug addiction caused by the use of the addictive painkiller fentanyl. The vaccine was created by a research team at the University of Houston, with the goal of blocking fentanyl from reaching the brain and eliminating the feeling of drug intoxication. Thanks to this new investment, Ovax is set to begin clinical trials in early 2025, offering hope for preventing relapse and aiding those struggling with drug addiction or overdose.

In addition to the University of Houston, the company behind Ovax is collaborating with various research groups working on ways to counter the effects of opioids, with the intention of turning their scientific discoveries into commercial products. The Ovax vaccine was initially announced in November 2022 and received funding from the US government, with an initial investment of over $760,000 towards research. Animal testing has shown promising results, reducing dependence on potentially addictive opioid painkillers without causing severe side effects.

The vaccine works by generating specific anti-fentanyl antibodies in the body, preventing the euphoric effects and increasing alertness typically experienced after taking the drug. Moreover, the vaccine does not interfere with other opioids, allowing individuals injected with Ovax to still receive treatment for pain with drugs like morphine. Fentanyl, a potent synthetic opioid often used in illegal drugs, poses a significant threat due to its strength – 50 times more potent than heroin and 100 times more potent than morphine, capable of causing death with just a small amount.

The United States is facing a growing opioid crisis, with over 100,000 deaths reported from opioid overdoses in 2021 according to the Centers for Disease Control and Prevention (CDC). Fentanyl poisoning is the leading cause of death among individuals aged 18-45

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