Space Biology on ISS
NASA
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Please send any correspondence to Shawna Byrd, SPACELINE Present Awareness Senior Editor, [email protected].
Get in touch with for articles to cite in the weekly lists: Authors at NASA Centers and NASA PIs—do you have an write-up that has lately published or will publish in the upcoming weeks inside a peer-reviewed journal and is in the scope of space life sciences? If so, send it our way! Send your write-up to the e-mail address described above. Articles received by Wednesday will seem inside that week’s list—articles received right after Wednesday will seem the following week.
Papers deriving from NASA help:
1
Faerman A, Clark JB, Sutton JP.
Neuropsychological considerations for lengthy-duration deep spaceflight.
Front Physiol. 2023 May well 1914:1146096. Evaluation.
https://doi.org/ten.3389/fphys.2023.1146096
Note: This write-up is aspect of Study Subject “Brains in Space: Effects of Spaceflight on the Human Brain and Behavior-Volume II” (https://www.frontiersin.org/investigation-subjects/47491/brains-in-space-effects-of-spaceflight-on-the-human-brain-and-behavior—volume-ii#overview). The Study Subject also incorporates articles from prior Present Awareness Lists #1,041 https://doi.org/ten.3389/fphys.2023.1141078 and #1,046 https://doi.org/ten.3389/fncir.2023.1135434. This write-up could be obtained on line without having charge.
Journal Influence Issue: 3.342
Funding: “Support from the Translational Study Institute for Space Wellness via NASA Cooperative Agreement NNX16AO69A is gratefully acknowledged. JS is supported by the Friedkin Chair for Study in Sensory Method Integration and Space Medicine at Baylor College of Medicine.”
two
Shelhamer M, Antonsen E, Reynolds R.
The have to have for a systems strategy in spaceflight wellness and medicine.
2023 IEEE Aerospace Conference. 2023 May well 15.
https://doi.org/ten.1109/aero55745.2023.10115773
PI: M. Shelhamer
Note: This write-up is a conference proceeding published by a peer-reviewed journal.
Journal Influence Issue: 0.88
Funding: “MS is supported by NASA 80NSSC19K0487.”
three
Shelhamer M, Gersh JR.
A mission architecture to integrate human and spacecraft functional functionality.
2023 IEEE Aerospace Conference. 2023 May well 15:1-eight.
https://doi.org/ten.1109/aero55745.2023.10115715
PI: M. Shelhamer
Note: This write-up is a conference proceeding published by a peer-reviewed journal.
Journal Influence Issue: 0.88
Funding: “MS is supported by NASA 80NSSC19K0487.”
four
Hilditch CJ, Pradhan S, Costedoat G, Bathurst NG, Glaros Z, Gregory KB, Shattuck NL, Flynn-Evans EE.
Sex variations in perceptions of sleep inertia following nighttime awakenings.
Sleep Adv. 20234(1):zpac043.
https://pubmed.ncbi.nlm.nih.gov/37193286
Note: This write-up could be obtained on line without having charge.
Journal Influence Issue: Not obtainable for this journal
Funding: “This operate was supported in aspect by the Naval Healthcare Study Center’s Naval Sophisticated Healthcare Improvement Plan (MIPR N3239820WXHN007) and the National Aeronautics and Space Administration Airspace Operations and Security Plan, Method Wide Security.”
five
Saint-Guillain M, Vanderdonckt J, Burny N, Pletser V, Vaquero T, Chien S, Karl A, Marquez J, Wain C, Comein A, Casla IS, Jacobs J, Meert J, Chamart C, Drouet S, Manon J.
Enabling astronaut self-scheduling applying a robust sophisticated modeling and scheduling method: An assessment for the duration of a Mars analogue mission.
Adv Space Res. 2023 Apr five. On line ahead of print.
https://doi.org/ten.1016/j.asr.2023.03.045
Note: From the abstract: “Human lengthy duration exploration missions (LDEMs) raise a quantity of technological challenges. This paper addresses the query of the crew autonomy: as the distances raise, the communication delays and constraints have a tendency to avert the astronauts from getting monitored and supported by a genuine time ground handle.”
Journal Influence Issue: 2.611
Funding: T. Vaquero and S. Chien are affiliated with NASA Jet Propulsion Laboratory. J. Marquez is affiliated with NASA Ames Study Center.
six
Schroeck H, Whitty MA, Martinez-Camblor P, Voicu S, Burian BK, Taenzer AH.
Anaesthesia clinicians’ perception of security, workload, anxiousness, and strain in a remote hybrid suite compared with the operating area.
Br J Anaesth. 2023 May well 16S0007-0912(23)00203-9. On line ahead of print.
https://pubmed.ncbi.nlm.nih.gov/37202262
Journal Influence Issue: 11.719
Funding: B.K. Burian is affiliated with NASA Ames Study Center.
7
Li M, Lee JD.
Modeling objective alignment in human-AI teaming: A dynamic game theory strategy.
Proc Hum Variables Ergon Soc Annu Meet. 2022 Oct66(1):1538-42.
https://doi.org/ten.1177/1071181322661047
PI: J.D. Lee
Note: This write-up is a meeting proceedings that published in peer-reviewed Sage journals. This write-up could be obtained on line without having charge.
Journal Influence Issue: 3.598
Funding: “This operate was supported by NASA Human Study Plan No. 80NSSC19K0654.”
eight
Buettmann EG, Chlebek C, Lockard CA, Clayton SW, Lewis KJ, Collins KH.
Post or perish? Social media methods for disseminating orthopedic investigation.
J Orthop Res. 2023 May well ten. On line ahead of print.
https://doi.org/ten.1002/jor.25588
PI: E.G. Buettmann
Note: This write-up could be obtained on line without having charge.
Journal Influence Issue: 3.103
Funding: “Dr. Evan Buettmann was supported by the Translational Study Institute for Space Wellness (TRISH) via Cooperative Agreement with NASA (NNX16AO69A). Dr. Kelsey Collins was supported by NIAMS (Grant K99AR078949).”
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Other papers of interest:
1
Almosa AS, Lockwood MB, Green SJ.
Effects of spaceflight on the human gastrointestinal tract microbiome.
J Indian Inst Sci. 2023 May well 23. Evaluation.
https://doi.org/ten.1007/s41745-023-00384-7
Note: From the abstract: “In this quick assessment, we summarize the present state of know-how on the impact of space travel on the human gut microbiome, which includes investigation styles that consist of animals (rodents), humans, and novel simulations. Experiments had been performed beneath circumstances of spaceflight, ground-primarily based, and analogous flight simulation.”
two
Ejova A, Searston RA, Stephens R, Semmler C.
Clear pondering in deep space: A guide by cognitive scientists.
In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Makes use of of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. 31-47.
https://doi.org/ten.1007/978-981-19-9462-three_three
three
Oxlad M, Whitburn S, Carter AJ.
Optimizing mission good results: A holistic strategy to choosing the most effective persons to travel to space.
In: de Zwart M, Henderson S, Culton J, Turnbull D, Srivastava A, eds. Human Makes use of of Outer Space: Return to the Moon. Singapore: Springer Nature Singapore, 2023. p. five-29.
https://doi.org/ten.1007/978-981-19-9462-three_two
four
Sakaki T, Koizumi T, Ikeido Y, Soga K, Wakabayashi K, Hoson T.
Raise in steryl glycoside levels and stimulation of lipid raft formation in azuki bean epicotyls beneath hypergravity circumstances.
Life Sci Space Res. 2023 Aug 2338:53-eight.
https://doi.org/ten.1016/j.lssr.2023.05.005
Note: A centrifuge was utilised in this study.
five
Lv W, Peng X, Tu Y, Shi Y, Song G, Luo Q.
YAP [Yes-associated protein] inhibition alleviates simulated microgravity-induced mesenchymal stem cell senescence through targeting mitochondrial dysfunction.
Antioxidants. 2023 Apr 2312(five):990.
https://doi.org/ten.3390/antiox12050990
Note: A 2D clinostat was utilised in this study. From the abstract: “Weightlessness in space leads to bone loss, muscle atrophy, and impaired immune defense in astronauts. Mesenchymal stem cells (MSCs) play critical roles in sustaining the homeostasis and function of the tissue. Having said that, how microgravity impacts the qualities MSCs and the associated roles in the pathophysiological adjustments in astronauts stay barely recognized.” This write-up is aspect of Subject “Advances in Astrobiology” (https://www.mdpi.com/subjects/T9B7L6S956). This write-up could be obtained on line without having charge.
six
Shamei A, Sóskuthy M, Stavness I, Gick B.
Postural adaptation to microgravity underlies fine motor impairment in astronauts’ speech.
Sci Rep. 2023 May well 2213:8231.
https://pubmed.ncbi.nlm.nih.gov/37217497
Note: From the write-up: “The authors declare that the information utilised inside this evaluation was obtained from publicly obtainable sources, and all investigation was completed in accordance with human investigation ethics recommendations and regulations. The National Aeronautics and Space Administration (NASA) delivers audio and video for a choice of missions via the public NASA photos archive, which includes audio and video files of Astronaut interviews for chosen missions. Audio files from every mission had been chosen for the reason that they function substantial speech information (among 70 and 120 s of speech) of astronauts straight away ahead of and right after their respective missions, permitting direct comparisons of vowel space ahead of and right after adaptations to microgravity. We evaluated vowel formants from 4 astronauts across 4 STS missions: (i) STS-129 (ii) STS-133, (iii) STS-134, and (iv) STS-135.” This write-up could be obtained on line without having charge.
7
Yue Y, Yang J-Q, Lu S-Y, Ge J, Nie H-Y, Liu K-G, Liu F, Li H, Yan H-F, Zhang T, Sun P-M, Sun H-W, Yang J-W, Zhou J-L, Cui Y.
Simulated microgravity altered the proliferation, apoptosis, and extracellular matrix formation of L929 fibroblasts and the transforming development aspect-β1/Smad3 signaling pathway.
Skin Res Technol. 2023 May well 829(five):e13341. On line ahead of print.
https://doi.org/ten.1111/srt.13341
Note: A rotary cell culture method was utilised in this study. This write-up could be obtained on line without having charge.
eight
Zhang Y, Huang H, Yao C, Sun X, He Q, Choudharyc MI, Chen S, Liu X, Jiang N.
Fresh Gastrodia elata blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-associated pathways.
Front Pharmacol. 2023 May well 314:1173920.
https://pubmed.ncbi.nlm.nih.gov/37205911
Note: Hindlimb unloading study. This write-up is aspect of Study Subject “Exploring the Important Targets and Compounds That Manipulate Brain Neurocircuits Against Mental Problems and Psychiatric” (https://www.frontiersin.org/investigation-subjects/44928/exploring-the-crucial-targets-and-compounds-that-manipulate-brain-neurocircuits-against-mental-issues-and-psychiatric#overview). The Study Subject also incorporates an write-up from prior Present Awareness List #1,050 https://doi.org/ten.3389/fphar.2023.1167398. More articles will be forthcoming and could be located in the hyperlink to the Study Subject. This write-up could be obtained on line without having charge.
9
Sim HJ, So HS, Poudel SB, Bhattarai G, Cho ES, Lee JC, Kook SH.
Osteoblastic Wls ablation protects mice from total physique irradiation-induced impairments in hematopoiesis and bone marrow microenvironment.
Aging Dis. 2023 Jun 114(three):919-36.
https://pubmed.ncbi.nlm.nih.gov/37191410
Note: This write-up could be obtained on line without having charge.
ten
Zhang Q, Gerweck LE, Cascio E, Gu L, Yang Q, Dong X, Huang P, Bertolet A, Nesteruk KP, Sung W, McNamara AL, Schuemann J.
Absence of tissue-sparing effects in partial proton FLASH irradiation in murine intestine.
Cancers (Basel). 2023 Apr 1315(eight):2269.
https://pubmed.ncbi.nlm.nih.gov/37190197
Note: This write-up could be obtained on line without having charge.
11
Waldbaum JDH, Xhumari J, Akinsuyi OS, Arjmandi B, Anton S, Roesch LFW.
Association among dysbiosis in the gut microbiota of principal osteoporosis individuals and bone loss.
Aging Dis. 2023 Apr 28. Evaluation.
https://pubmed.ncbi.nlm.nih.gov/37199579
Note: This write-up could be obtained on line without having charge.
12
Badakva AM, Miller NV, Zobova LN.
Integration of vestibular, visual, and proprioceptive inputs in the cerebral cortex for the duration of movement handle.
Hum Physiol. 2023 Apr 2749(two):176-82. Evaluation.
https://doi.org/ten.1134/S0362119722600515
13
Kelly KR, Palombo LJ, Jensen AE, Bernards JR.
Efficacy of closed cell wet-suit at numerous depths and gas mixtures for thermoprotection for the duration of military instruction dives.
Front Physiol. 2023 May well 2414:1165196.
https://doi.org/ten.3389/fphys.2023.1165196
Note: This write-up could be obtained on line without having charge.
