High protein diets have long been associated with cardiovascular disease, but until now, the exact mechanism by which excessive protein consumption can lead to arterial disease was not fully understood. In a new study published in Nature Metabolism, a team of researchers led by the University of Pittsburgh sheds light on the harmful effects of high-protein diets on heart and blood vessels.
Protein is an essential nutrient for humans, but current recommendations suggest that less than 20 percent of total energy should come from protein for individuals under the age of 65. While Finland’s population meets the recommended protein intake, approximately 20 percent exceed it. Men tend to consume more protein than women, and diets rich in animal-based foods like red meat, eggs, and milk are high in leucine, an amino acid that plays a crucial role in arterial disease formation.
Researchers found that excessive protein consumption can activate immune cells associated with arterial disease. Specifically, high levels of leucine in the bloodstream can lead to inflammation and damage to immune cells responsible for clearing cellular waste. Over time, this accumulation of waste under the artery wall lining can lead to plaque buildup, which increases the risk of heart attack and stroke.
While more research is needed to fully understand the implications of high-protein diets on cardiovascular health, these findings suggest that it may be necessary to limit animal-based food intake and focus on plant-based sources of protein like beans or lentils instead. It is also important for individuals to maintain a balanced diet while avoiding excessive protein intake.
